NAAT may also be performed in smear-negative patients.take at least 1 respiratory sample with Health Canada-approved or -validated in-house NAAT in all new, smear-positive cases.nucleic acid amplification testing (NAAT).rapid molecular tests for DST should be reserved for patients with a high pretest probability of multi-drug-resistant tuberculosis.phenotypic DST should be routinely performed for all first positive culture isolates obtained from each new tuberculosis case.culture results typically take 2 to 8 weeks.every specimen sent for smear microscopy should be set up for culture in 1 solid and 1 liquid medium.mycobacterial culture and phenotypic drug sensitivity testing (DST).same-day collection may be considered to reduce patient drop-out.sputum (phlegm) specimens should be collected a minimum of 1 hour apart.everyone with suspected tuberculosis should undergo testing with at least 3 concentrated fluorescent smears.it should be followed by microbiological tests for tuberculosis.chest radiography cannot provide a conclusive diagnosis on its own.In Canada, the standard testing algorithm for active tuberculosis includes the following tests: do a complete medical history and examinationĮvery effort should be made to obtain a microbiological diagnosis.There are 3 steps in diagnosing active tuberculosis disease: when an individual is considered to be at high risk.in everyone with signs and symptoms of tuberculosis.Testing for active tuberculosis is indicated: not recommended for routine diagnosis of latent tuberculosis infection.it takes 3 to 8 weeks after exposure for the skin test to become positiveīlood test (interferon gamma release assay)Ī blood test for latent tuberculosis infection is:. recently been infected by a person with active tuberculosis disease:.infected with other tuberculosis -like germsĪ negative test result can happen even if a patient has tuberculosis bacteria in their body.vaccinated with Bacille Calmette-Guérin vaccine (BCG).In the presence of symptoms or abnormal chest X-ray, sputum for acid-fast bacteria smear and culture should be taken.Ī positive test can happen even if a patient does not have a latent tuberculosis infection. assess signs and symptoms suggestive of possible active tuberculosis disease.do more tests to find out if the patient has active tuberculosis disease.investigate further to rule out a false positive.If a patient has a positive test result, you may need to: Inform your patient if the test is positive or negative. A measurement of more than 5 mm could be considered a positive result. The area of hardness (not redness) should be objectively measured with a ruler. The spot where the needle was injected will develop an area of redness with possible hardening (induration). If the patient is infected with tuberculosis, a skin reaction will occur within 48 to 72 hours. measuring the patient's reaction 2 or 3 days after the test.injecting a small amount of non-infectious tuberculosis protein under the surface of the patient's skin using a small needle.Tuberculosis skin testĪ tuberculin skin test (also called a Mantoux tuberculin test) is used to see if you have been exposed to tuberculosis and perhaps have latent tuberculosis infection or active tuberculosis disease. Preference and exceptions are outlined in the Canadian Tuberculosis Standards. blood test (interferon gamma release assay).There are 2 accepted tests for identification of latent tuberculosis infection: There are 2 types of tuberculosis infection: This means that cases must be reported to the corresponding provincial and territorial department of health. Tuberculosis is a legally reportable disease in every Canadian province and territory. Tuberculosis usually affects the lungs, but may also affect other organs, such as the: 5% will have a reactivation and develop active tuberculosis at any point after initial infection.about 90% will never develop active tuberculosis disease.about 95% will develop latent tuberculosis infection, of which:.about 5% will develop active tuberculosis disease within 18 to 24 months.Tuberculosis is an infectious disease caused by the bacteria Mycobacterium tuberculosis. What health professionals need to know about tuberculosis What health professionals need to know about tuberculosis.
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